/* style global */
*,
*::before,
*::after,
body {
    /* J'ai supprimé ces deux styles car ils interfèrent avec mdb (décalage de l'icône de DAtePicker). A coordonner avec Eric si il est nécessaire de les remettre */
    /* padding: 0;
    margin: 0; */
    list-style: none;
    text-decoration: none;
}

body {
    overflow-x: hidden;
}

.flex{display:flex;}
.flex-col{flex-direction:column;}
.flex-row{flex-direction:row;}
.items-center{align-items: center;}
.relative{position:relative !important;}
.absolute{position:absolute !important;}
.my-auto{margin-top:auto;margin-bottom:auto;}
.mx-auto{margin-left:auto;margin-right:auto;}
.gap-10{gap:10px;}
.gap-20{gap:20px;}
.w-full{width:100%;}
.h-full{height:100%;}
.size-full{width:100%;height:100%;}
.bg-cover{background-size: cover;}
.bg-center{background-position:center center;}

.uppercase {
    text-transform: uppercase;
}

.italic{
    font-style: italic;
}

.float_l_santor{
    float: left;
}

.gap5_santor{
    gap: 5px;
}

.flex_santor{
    display: flex;
}

.justify_between_santor{
    justify-content: space-between;
}

.justify_center_santor{
    justify-content: center;
}

.flex_col_santor {
    display: flex;
    flex-direction: column;
}

.flex_row_santor{
    display: flex;
    flex-direction: row;
}

.mr_santor{
    margin-right: 2em;
}

.m0_santor{
    margin: 0;
}

.my1_santor{
    margin-top: 1em;
    margin-bottom: 1em;
}

.mb1_santor{
    margin-bottom: 1em;
}

.mb2_santor{
    margin-bottom: 2em;
}

.mb3_santor{
    margin-bottom: 3em;
}

.mb4_santor{
    margin-bottom: 4em;
}

.m1{
    margin: 1em;
}

.bold_santor{
    font-weight: bold !important;
}

.text_center_santor{
    text-align: center;
}

.item_center_santor{
    align-items: center;
}

.mw_santor {
    max-width: 100%;
}

.img_tncb {
    width: 100%;
}

.mt_santor {
    margin-top: 1em;
}

.color_white {
    color: white !important;
}

.color_black{
    color: black !important;
}

a.liens-interet {
    color: #c6027e;
    font-weight: bolder;
    text-decoration: none;
    cursor: zoom-in;
}
.author_biblio a.liens-interet {
    font-size: 13px;
}

.btn {
    background-color: #c6027e;
    color: #fff;
    text-decoration: none;
    padding: 5px 20px;
    display: block;
    text-align: center;
    text-transform: uppercase;
    font-family: myriad-pro, sans-serif;
    font-weight: 400;
    font-style: normal;
    display: flex;
    align-items: center;
    font-size: 14px;
}

/* style reseaux sociaux */
.reseaux {
    background-color: #e1e1e1;
}

.reseaux ul {
    list-style: none;
    display: flex;
    justify-content: end;
    align-items: center;
    gap: 10px;
    padding: 5px 20px;
    max-width: 1380px;
    margin: 0 auto;
}

.reseaux img {
    width: 25px;
}

/* style logo, partenaire, connexion, barre de recherche */
header .row2 {
    max-width: 1380px;
    margin: 0 auto;
    display: flex;
    justify-content: space-between;
    padding: 20px;
    gap: 20px;
}

header .row2 .col1 {
    display: flex;
    align-items: center;
}

header .row2 .logo img {
    width: 100%;
    max-width: 500px;
}

header .row2 .partenaire {
    background-color: #f9f9f9;
    display: flex;
    align-items: center;
    padding: 20px;
    margin-left: 20px;
    border-left: 1px solid #c4c4c4;
    color: #333333;
    font-family: myriad-pro, sans-serif;
    font-weight: 600;
    font-style: normal;
    font-size: 14px;
}

header .row2 .partenaire a {
    text-decoration: none;
    color: #444444;
    font-weight: normal;
    display:flex;
    flex-direction: column;
    align-items: left;
    gap:5px;
}

header .row2 .partenaire a span{
    font-size:12px;
}

header .row2 .partenaire a img{
    width:100%;
    max-width:180px;
}

header .row2 .connexion {
    display: flex;
    gap: 10px;
    margin-bottom: 10px;
}

header .row2 .search {
    display: flex;
}

header .row2 .search img {
    width: 100%;
    max-width: 10px;
}

header .row2 .search input {
    width: 100%;
    padding: 5px;
    border-radius: 0;
    border: 2px solid #cdcdcd;
    margin-right: -2px;
    color: #cdcdcd;
}

header .row2 .search button {
    width: 50px;
    display: flex;
    justify-content: center;
    align-items: center;
    background-color: transparent;
    border-radius: 0;
    border: 2px solid #cdcdcd;
}

/* style side menu */
.dropdown-collapse {
    max-height: 0;
    overflow: hidden;
    opacity: 0;
    transition: max-height 0.3s ease, opacity 0.3s ease;
}

.dropdown-collapse.active {
    max-height: 500px;
    opacity: 1;
    transition: max-height 0.3s ease, opacity 0.3s ease;
}

.dropdown-header.active  {
    background-color: #32373c;
}

.dropdown-header.active button  {
    color: #fff;
}

.dropdown-header {
    position: relative;
}

.dropdown-header::after {
    content: "";
    position: absolute;
    top: 0;
    right: 20px;
    bottom: 0;
    margin: auto;
    background-image: url(https://static.mediscoop.net/images_communes/realites_onco/arrow-down_b.svg);
    background-size: 30px;
    width: 30px;
    height: 30px;
    background-repeat: no-repeat;
    transform: rotate(0);
}

.dropdown-header.active::after {
    transform: rotate(-180deg);
    transition: transform 0.3s ease;
    background-image: url(https://static.mediscoop.net/images_communes/realites_onco/arrow-down.svg);
}

.mb-auto
{
    margin-bottom: auto !important;
}

.dropdown-body {
    padding: 10px;
}

.dropdown-body li {
    padding: 10px;
    cursor: pointer;
}

.dropdown-body li:hover {
    background-color: #e1e1e1;
}

header .dropdown {
    margin: 20px 0;
}

header .side_menu {
    position: fixed;
    z-index: 1000000;
    left: -2000px;
    width: 100%;
    top: 0;
    bottom: 0;
    height: 100vh;
    overflow: hidden;
    background-color: #ffffff;
    transition: 0.5s;
    padding: 0;
    margin: 0;
    overflow: hidden;
    width: 100vw;
    height: 100vh;
    height: var(--app-height) !important;
}

header .side_menu .reseaux {
    padding: 20px 0;
    display: flex;
    justify-content: center;
    gap: 10px;
}

header .side_menu .entete {
    display: flex;
    justify-content: space-between;
    align-items: center;
    background-color: #32373c;
    padding: 10px 20px;
}

header .side_menu .entete .btn_close {
    display: flex;
    justify-content: end;
    align-items: center;
}
header .side_menu .entete .btn_close img {
    width: 35px;
}
header .side_menu .entete .logo {
    width: 100%;
    display: block;
}
header .side_menu .entete .logo img {
    width: 100%;
    max-width: 200px;
}
header .side_menu .dropdown-body ul {
    padding: 0;
    margin: 0;
}
header .side_menu .dropdown-body ul li a {
    color: #212529;
    text-decoration: none;
    display: block;
    width: 100%;
    height: 100%;
}

header .side_menu .dropdown-header {
    padding: 20px;
    display: flex;
    align-items: center;
    border-bottom: 1px solid #cdcdcd;
    border-top: 1px solid #cdcdcd;
    margin-bottom: -1px;
    cursor: pointer;
}

header .side_menu .dropdown-button {
    background-color: transparent;
    border: none;
    text-transform: uppercase;
}
header .side_menu .dropdown-button:focus {
    box-shadow: none;
}
header .side_menu.open {
    left: 0;
}

/* style barre de navigation */
nav .list {
    display: flex;
}

nav {
    background-color: #32373c;
    max-width: 1340px;
    margin-left: auto;
    margin-right: auto;
    margin-bottom: 20px;
}

nav .list {
    display: flex;
    font-size: 12px;
    justify-content: center;
    padding: 0;
    max-width: 1290px;
    margin: 0 auto;
}

nav .item {
    text-align: center;
    border: 1px solid #fff;
    border-top: none;
    margin-right: -1px;
    margin-bottom: -1px;
    position: relative;

}

nav .item img {
    width: 10px;
}

nav .item a,
nav .item > div {
    color: #fff;
    text-transform: uppercase;
    font-family: myriad-pro, sans-serif;
    font-weight: 700;
    font-style: normal;
}

nav .item .dropdown a {
    text-transform: none;
    text-align: left;
}

nav .item > a,
nav .item > div {
    padding: 10px;
    display: flex;
    justify-content: center;
    gap: 5px;
    font-weight: 700;
    font-size: 11px;
}

nav .dropdown.hover {
    position: absolute;
    z-index: 1000;
    padding: 10px 0 0 0;
    margin: 0;
    width: 100%;
    min-width: 300px;
    top: 100%;
    left: 0;
    opacity: 0;
    transition: opacity 0.3s ease, max-height 0.3s ease;
    max-height: 0;
    overflow: hidden;
    pointer-events: none;
}

nav .item ul li:first-child {
    padding-top: 10px;
}

nav .item ul li {
    padding-right: 10px;
    padding-left: 10px;
    padding-bottom: 0;
    background-color: #32373c;
}

nav .item ul li:last-child {
    padding-bottom: 10px;
}

nav .item ul li a {
    padding: 10px;
    display: block;
}

.item:hover .dropdown.hover {
    opacity: 1;
    max-height: 500px;
    pointer-events: auto;
}

nav .item ul li:hover a {
    background-color: #62686f;
}


/* style news */
.news {
    background-color: #e0e9ff;
    padding: 20px 0;
    margin-bottom: 20px;
}

.news .row1 {
    max-width: 1380px;
    margin: 0 auto;
    padding: 0 20px;
    display: flex;
    gap: 30px;
}

.nouveautes {
    width: 100%;
}

.nouveautes .swiper-slide {
    display: flex;
    justify-content: center;
    align-items: center;
    flex-direction: column;
    position: relative;
}

.nouveautes .swiper-slide img {
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    margin: auto;
    z-index: -1;
    height: 100%;
}

.nouveautes .swiper-slide h2 {
    font-family: myriad-pro, sans-serif;
    font-weight: 600;
    font-style: normal;
    font-size: 24px;
    margin-bottom: 30px;
    color: #fff;
    letter-spacing: 2px;
}

.swiper-pagination {
    margin-bottom: 20px;
}

.nouveautes .swiper-button-next {
    background-image: url("https://static.mediscoop.net/images_communes/realites_onco/arrow_right.svg");
    background-repeat: no-repeat;
    background-position: center;
}

.swiper-button-next{
    right: 20px;
}

.swiper-button-prev {
    left: 20px;
}

.swiper-button-prev {
    background-image: url("https://static.mediscoop.net/images_communes/realites_onco/arrow_left.svg");
    background-repeat: no-repeat;
    background-position: center;
}

.swiper-button-next:after,
.swiper-button-prev:after {
    display: none;
}

.swiper-pagination-bullet,
.swiper-pagination-bullet-active {
    opacity: 1;
    background-color: #fff;
}

.swiper-pagination-bullet-active {
    background-color: #c6027e;
}

.news .col2 {
    width: 100%;
    max-width: 30%;
    display: flex;
    flex-direction: column;
    gap: 20px;
}

.news .item {
    position: relative;
    padding: 20px;
    height: 100px;
}

.itemRight{
    background-image: url("https://static.mediscoop.net/images_communes/realites_onco/bg_cascli.png");
    background-repeat: no-repeat;
    background-size: cover;
    color: white;
    margin-bottom: 40px;
}

.article-title-item{
    background-color : #C6027E;
    width:fit-content;
    color: white;
    padding: 8px;
    font-size: 0.8em;
}

.news .item:nth-child(1) {
    background-image: url("https://static.mediscoop.net/images_communes/realites_onco/bg_cascli.png");
    background-repeat: no-repeat;
    background-size: cover;
}

.news .item:nth-child(2) {
    background-image: url("https://static.mediscoop.net/images_communes/realites_onco/bg_fiche.png");
    background-repeat: no-repeat;
    background-size: cover;
}

.news h3 {
    text-transform: uppercase;
    color: #fff;
    font-family: myriad-pro, sans-serif;
    font-weight: 600;
    font-style: normal;
    font-size: 16px;
    margin-bottom: 10px;
}

.news a {
    color: #fff;
}

.news .item a.btn {
    justify-content: center;
    position: absolute;
    z-index: 2;
    bottom: 0;
    right: 0;
    font-size: 20px;
    padding: 2px 10px;
}

.bouton_cas_clinique_acces{
    background-color: #C6027E;
    padding: 10px;
}

/* style global content */
.global-content {
    display: flex;
    justify-content:space-between;
    max-width: 1380px;
    margin: 0 auto 0;
    padding: 0 20px;
}

.global-content .col1 {
    width: 100%;
    padding-right: 30px;
    margin-right: 30px;
    border-right: 1px solid #cdcdcd;
}

.global-content .col1 .row1 {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 20px;
    margin-bottom: 50px;
}

.global-content .col1 .illus {
    background-repeat: no-repeat;
    background-size: cover;
    height: 209px;
    position: relative;
    display: block;
}

.global-content .col1 .illus.rose {
    background-color: #c6027e;
}

.global-content .col1 .illus.rose {
    display: flex;
    justify-content: center;
    align-items: center;
    flex-direction: column;
}

.global-content .col1 .illus.rose h3 {
    color: #fff;
    text-transform: uppercase;
}

.global-content .col1 .illus.rose a {
    color: #c6027e;
    background-color: #fff;
    text-transform: uppercase;
}

.global-content .col1 .illus span {
    position: absolute;
    top: 0;
    left: 0;
}

.global-content .col1 h3 {
    color: #c6027e;
    margin: 10px 0;
    text-transform: uppercase;
    font-family: myriad-pro, sans-serif;
    font-weight: 700;
    font-style: normal;
    font-size: 11px;
}

.global-content .col1 h3 a {
    color: #c6027e;
}

.global-content .col1 p {
    color: #868686;
    font-family: myriad-pro, sans-serif;
    font-weight: 400;
    font-style: normal;
    font-size: 15px;
    text-align: left;
}

.global-content .col1 .row2 .titre {
    position: relative;
    padding: 0 20px 15px 15px;
}

.global-content .col1 .row2 h3 {
    margin: 0;
}

.global-content .col1 .row2 .titre img {
    position: absolute;
    left: 0;
    bottom: 0;
    width: 30px;
}

.global-content .col2 {
    width: 100%;
    max-width: 30%;
}

.global-content .col2 .item {
    background-color: #e0e9ff;
    height: 220px;
    width: 100%;
    margin-bottom: 10px;
}

.title_text_item{
    color: #C6027E;
}

.text_item{
    margin-top: 10px;
    font-size: 0.8em;
    line-height: 13px;
}

.big-item{
    margin-bottom: 40px;
}

.global-content .col1 .row2 .item {
    margin-bottom: 30px;
}

.global-content .col1 .row2 h3 {
    font-size: 20px;
}

.global-content .col1 .row2 .img {
    position: relative;
}

.global-content .col1 .row2 .img img {
    width: 100%;
}

.global-content .col1 .row2 .img a {
    position: absolute;
    bottom: 0;
    right: 0;
    font-size: 12px;
}

.global-content .col1 .row3 {
    background-image: url("../images/visuel-cote-biblio-8674f72351ebaa7dc9c650e7f7d2dfe7.jpg");
    
    padding: 30px;
    display: flex;
    justify-content: space-between;
    align-items: center;
    gap: 20px;
    margin: 50px 0;
    margin-top: 30px;
}

.global-content .col1 .row3 h3 {
    color: #fff;
}

.global-content .col1 .row3 a {
    background-color: #fff;
    color: #c6027e;
}

/* style footer */
footer {
    background-color: #3c3c3b;
    padding: 30px 20px;
}

footer,
footer a {
    color: #fff;
    font-family: myriad-pro, sans-serif;
    font-weight: 400;
    font-style: normal;
    font-size: 12px;
}

.footer {
    max-width: 1380px;
    margin: 0 auto;
    padding: 20px;
    gap: 20px;
}

.footer .row1 {
    display: grid;
    grid-template-columns: repeat(3, 1fr);
    gap: 50px;
    margin-bottom: 50px;
}

.footer .row1 .logo {
    margin-bottom: 20px;
    display: block;
}

.footer .row1 ul li {
    margin-bottom: 10px;
    padding-bottom: 10px;
    border-bottom: 1px solid #fff;
}

.footer .row2 {
    display: flex;
    justify-content: center;
    align-items: center;
    gap: 10px;
}

.file-ariane
{
    background-color: rgb(238, 234, 234);
    margin: auto;
    padding: 5px 160px;
    margin-top: -20px;
}


.title
{
    max-width: 1160px;
    border-left: solid rgb(230,0,118);;
    border-width: 10px;
    margin: 40px auto 30px;
    padding: 0 20px;
    font-size: 20px;
    font-weight: bolder;
}

.image-abo
{
    width: 35% !important;
}

.feuille
{
    color: #e54e53 !important;
    font-weight: 600 !important;
}

.text-abo
{
    width: 80% !important;
    margin-bottom: 0;
}

.question-div
{
    font-weight: 600;
    text-transform: uppercase;
    font-size: 14px;
    line-height: 32px;

}

.groupe-text-contact{
    padding: 5px 14px;  
    line-height: 25px;
    font-weight: 300;
    
    font-size: 13px;
    margin: 20px 0;
    border-bottom: 1px solid #d9d9d9;
    border-top: 1px solid #d9d9d9;
    background-color: #f9f9f9;
}

.mt{
    margin-top: 2em !important;
}

.mt1{
    margin-top: 1em !important;
}

.bo{
    font-weight: bold;
}

.jifro{
    display: flex;
    flex-direction: column;
    width: 23%;
    align-items: center;
}

.nb_et_titre{
    display: flex;
    flex-direction: row;
    gap: 1em;
}

.nb{
    display: flex;
    flex-direction: column;
    gap: 5px;
}

.second_titre{
    display: flex;
    flex-direction: column;
    gap: 5px;
}

.table_matiere{
    background-color: lightgray;
    padding: 1em;
}

.generalie_exemple{
    display: flex;
    flex-direction: column;
    gap: 5px;
}

.point-fort {
    box-shadow: -4px 4px 8px rgba(0, 0, 0, 0.3);
    padding: 20px; 
    margin-bottom: 3em;
}

.point-fort ul {
    margin: 0;
    padding: 0;
}

.point-fort li {
    margin-bottom: 10px;
    display: flex;
    flex-direction: row; 
}

.point-fort h3 {
    color : white !important;
    font-size: 20px !important;
    font-weight: lighter !important;
}

.tooltip-inner {
    text-align: left !important;
  }

.point-fort .header-point-fort {
    background-color: rgb(148,184,227);
    color : white; 
    box-shadow: 4px 4px 8px rgba(0, 0, 0, 0.35);
    padding: 10px;
    max-width: 60%;
    margin-bottom: 20px;
}


.point-fort p {
    margin: 0;
}

.sec_article{
    margin-top: 1em !important;
    margin-bottom: 1em !important;
}

.renom
{
    font-weight: bold;
}

.mention p
{
    font-size: 16px !important;
}

.mention h3
{
    font-size: 19px !important;
    color: #212529 !important;
}

.mention .imp
{
    margin: 0 !important;
}

.biblio_img_banner11{
    max-width: 11em;
}

.biblio_img_banner2{
    width: 11em;
    height: 6em;
    background-image: url("../images/bibliographie/visuel-biblio-onco-gyneco-92fd374d3e51b0cba665947b42da570c.jpg");
    background-repeat: no-repeat;
    background-size: cover;
}

.biblio_img_banner3{
    width: 11em;
    height: 6em;
    background-image: url("../images/bibliographie/visuel-biblio-onco-thoracique-489c7804a6812865042fb49ad93c536d.jpg");
    background-repeat: no-repeat;
    background-size: cover;
}



.banner_biblio_img{
    background-color: rgb(198, 2, 126);
    padding: 3px;
    font-size: 0.8em;
    color: white;
    text-align: center;
}

.modal-dialog #fast_login_form_div > div {
    margin: 0 !important;
}

.modal-dialog #fast_login_form_div button,
.modal-dialog #fast_login_form3 button,
.modal-dialog #fast_login_box2 button {
    justify-content: center !important;
}

.modal-dialog #fast_login_box2 button {
    margin-bottom: 20px;
}

.modal-header {
    background-color: #c6027e !important;
}

.modal-header .btn-close {
    margin: 0 !important;
    padding: 0 !important;
}

.select-option.selected.disabled {
    height: 0 !important;
}

@media screen and (max-width:1080px) {
    .global-content .ligne.métastasique {
        flex-direction: column;
        justify-content: center;
    }

    .global-content .ligne.métastasique .image-abo {
        margin-bottom: 20px;
    }
}



@media screen and (max-width:790px) {
    .global-content .col1 {
        border: none;
        padding-right: 0;
    }

    .reseaux {
        display: none;
    }

    header .row2 {
        flex-direction: column;
    }

    header .row2 .col1 {
        justify-content: center;
    }

    header .row2 .connexion {
        justify-content: end;
    }

    header .row2 .partenaire {
        font-size: 12px;
    }

    .btn {
        font-size: 12px;
    }

    nav .item {
        display: none;
    }

    nav .item.menu {
        display: block !important;
        padding: 10px;
        cursor: pointer;
    }

    nav .item.menu img {
        width: 25px;
    }

    .news .row1 {
        flex-direction: column;
        gap: 20px;
    }

    .nouveautes {
        height: 200px;
    }

    .nouveautes .swiper-slide img {
        width: 100%;
    }

    .news .col2 {
        max-width: 100%;
    }

    .news h3 {
        font-size: 16px;
    }

    .news .item {
        padding: 10px;
        height: 70px;
    }

    .global-content {
        flex-direction: column;
    }

    .global-content .col1 .illus {
        height: 100px;
    }

    .global-content .col2 {
        max-width: 100%;
        display: grid;
        grid-template-columns: 1fr 1fr;
        gap: 20px;
        margin-bottom: 40px;
    }

    .global-content .col2 .item {
        margin-bottom: 0;
        height: 200px;
    }
}

.large_groupe_article {
    max-width: 100%;
}

.groupe_article {
    margin-top: 2em;
    display: flex;
    justify-content: space-between;
    flex-direction: column;
}

@media (min-width: 1050px) {
    .groupe_article {
        flex-direction: row; 
    }
}


    .groupe_div_img1{
        width: 150px;
    }

    .groupe_img{
        width: 100%;
    }

    .titre_auteur{
        display: flex;
        flex-direction: column;
    }

    .groupe_jifro{
        display: flex;
        flex-direction: column;
        justify-content: space-around;
    }

    @media (min-width: 1050px) {
        .groupe_jifro {
            flex-direction: row; 
        }
    }

    
@media screen and (max-width:600px) {
    header .row2 .col1 .logo {
        display: flex;
        align-items: center;
    }

    header .row2 .partenaire {
        padding: 10px;
        margin-left: 10px;
    }

    .nouveautes .swiper-slide h2 {
        text-align: center;
        font-size: 16px;
        padding: 0 20px;
    }

    .global-content .col1 .row1 {
        grid-template-columns: 1fr;
    }

    .global-content .col1 .row3 {
        flex-direction: column;
        padding: 30px 20px;
    }

    .global-content .col1 h3 {
        text-align: center;
    }

    .footer .row1 {
        grid-template-columns: 1fr;
        gap: 30px;
        margin-bottom: 20px;
    }

    .footer .row1 .logo img {
        max-width: 250px;
    }

    footer .row2 li {
        text-align: center;
    }

    
}

@media screen and (max-width: 680px) {
    .global-content .col2 {
        grid-template-columns: 1fr;
    }

    .global-content .col2 > div img {
        flex: 1;
    }

    .global-content .col2 > div div {
        flex: 1;
    }
}

@media screen and (max-width: 450px) {
    header .row2 .col1 {
        flex-direction: column;
    }

    header .row2 .partenaire {
        margin-left: 0;
        border: 0;
    }

    header .row2 .logo img {
        width: 100% !important;
        max-width: 300px;
    }
}

@media screen and (min-width: 1800px)
{
    .side_menu {display:none ;}
}